3.4.22.6: chymopapain

This is an abbreviated version, for detailed information about chymopapain, go to the full flat file.

Reaction

Similar to that of papain =

Synonyms

Chymopapain, chymopapain A, chymopapain B, chymopapain isoform II, chymopapain isoform III, chymopapain isoform IV, Chymopapain S, EC 3.4.4.11, More, papaya proteinase II, PPII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.6 chymopapain

General Stability

General Stability on EC 3.4.22.6 - chymopapain

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
during purification, the thiol function of the Cys residues are protected either as mixed disulfides with cysteamine or 2-thiopyridone or as S-sulfenylthiosulfate derivative or after blocking with PCMB
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freeze-drying causes 7% loss of activity
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mercury prevents both irreversible oxidation and autocatalysis
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PEG 20000 destabilizes chymopapain
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