3.4.21.B41: kallikrein 10

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For detailed information about kallikrein 10, go to the full flat file.

Reaction

proteolytic cleavage of polypeptides =

Synonyms

hK10, human kallikrein 10, K10, kallikrein 10, kallikrein-like protein 1, kallikrein-related peptidase 10, KLK-L1, KLK10, NES1, prostase, S01.246, tissue kallikrein-related peptidase 10

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B41 kallikrein 10

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Results	in table
1	Activating Compound
3	AA Sequence
8	Application
2	CAS Registry Number
8	Cloned(Commentary)
455	Disease/ Diagnostics
3	Expression
5	General Information
1	Inhibitors
4	Localization
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
28	Organism
2	Protein Variants
3	Purification (Commentary)
1	Reaction
7	Reaction Type
28	Reference
83	Source Tissue
8	Substrates and Products (Substrate)
47	Synonyms

Expression

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Expression on EC 3.4.21.B41 - kallikrein 10

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

frequent transcriptional inactivation of kallikrein 10 gene by CpG island hypermethylation in non-small cell lung cancer, overview. Restoration of KLK10 expression by 5-Aza-dC treatment

Homo sapiens

Q6ICR6

707999

KLK10 expression is significantly higher in cancerous than in normal colorectal tissues

Homo sapiens

-

718439

the enzyme is up-regulated in colorectal cancer, stepwise expression increase from metaplasia to dysplasia and invasive tumors, significantly increased enzyme expression in early invasive cancer, overview

Homo sapiens

O43240

731898