3.4.21.B41: kallikrein 10

This is an abbreviated version!
For detailed information about kallikrein 10, go to the full flat file.

Reaction

proteolytic cleavage of polypeptides =

Synonyms

hK10, human kallikrein 10, K10, kallikrein 10, kallikrein-like protein 1, kallikrein-related peptidase 10, KLK-L1, KLK10, NES1, prostase, S01.246, tissue kallikrein-related peptidase 10

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B41 kallikrein 10

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Results	in table
1	Activating Compound
3	AA Sequence
8	Application
2	CAS Registry Number
8	Cloned(Commentary)
455	Disease/ Diagnostics
3	Expression
5	General Information
1	Inhibitors
4	Localization
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
28	Organism
2	Protein Variants
3	Purification (Commentary)
1	Reaction
7	Reaction Type
28	Reference
83	Source Tissue
8	Substrates and Products (Substrate)
47	Synonyms

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Cloned on EC 3.4.21.B41 - kallikrein 10

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

DNA and amino acid sequence determination, in vitro translation

Homo sapiens

O43240

647362

expressed in COS-7 cells and 76R-30 cells

Homo sapiens

-

678524

expressed in Escherichia coli

Homo sapiens

-

681167

expressed in MCF-10A, MDA-MB-468 and T-47D cell lines

Homo sapiens

-

678530

expressed in Pichia pastoris

Homo sapiens

-

679256

gene (CANFA)KLK10, DNA and amino acid sequence determination and analysis, sequence comparison with the human gene, detailed overview

Canis lupus familiaris

D2IJU0

709783

gene KLK10, determination of frequency and functional significance of KLK10 hypermethylation in non-small cell lung cancer cells, mRNA expression and methylation status of KLK10 in 78 pairs specimens, overview

Homo sapiens

Q6ICR6

707999

gene KLK10, located at 19q13.3-q13.4, quantitative real-time PCR expression analysis, determination of DNA hypermethylation status of KLK10 in hepatocellular carcinoma cell lines and clinical samples, DNA methylation profiles, overview. Ectopic expression of KLK10 enhances drug sensitivity of HuH7 cells

Homo sapiens

-

708585