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Literature summary for 3.4.21.B41 extracted from

  • Zhang, Y.; Song, H.; Miao, Y.; Wang, R.; Chen, L.
    Frequent transcriptional inactivation of Kallikrein 10 gene by CpG island hypermethylation in non-small cell lung cancer (2010), Cancer Sci., 101, 934-940.
    View publication on PubMed

Application

Application Comment Organism
diagnostics KLK10 methylation can be used as a biomarker for non-small cell lung cancer Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
gene KLK10, determination of frequency and functional significance of KLK10 hypermethylation in non-small cell lung cancer cells, mRNA expression and methylation status of KLK10 in 78 pairs specimens, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6ICR6 gene KLK10
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Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell lung adenocarcinoma cell line Homo sapiens
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lung
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Homo sapiens
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non-small cell lung cancer cell KLK10 is significantly downregulated as compared to non-cancer samples. CpG island hypermethylation of KLK10 is detected in 46.2% of non-small cell lung cancer tissues Homo sapiens
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Synonyms

Synonyms Comment Organism
KLK10
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens frequent transcriptional inactivation of kallikrein 10 gene by CpG island hypermethylation in non-small cell lung cancer, overview. Restoration of KLK10 expression by 5-Aza-dC treatment down