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3.4.21.B40: kallikrein 9

This is an abbreviated version!
For detailed information about kallikrein 9, go to the full flat file.

Word Map on EC 3.4.21.B40

Reaction

proteolytic cleavage of polypeptides, preferential cleavage site at paired basic amino acid residues =

Synonyms

EGF-binding protein, EGF-BP, EGF-BP C, epidermal growth factor urogastrone, epidermal growth factor-binding protein, epidermal growth factor-binding protein type C, GK-9, high molecular weight epidermal growth factor, hk9, HMW-EGF, human tissue kallikrein 9, K9, kallikrein 9, kallikrein-related peptidase 9, KLK-S3, KLK9, mGK-9, mK9, mouse kallikrein 9, S01.307, S3 kallikrein, SEV, submandibular enzymatic vasocontrictor, tissue kallikrein, tissue kallikrein 9

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B40 kallikrein 9

Inhibitors

Inhibitors on EC 3.4.21.B40 - kallikrein 9

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Aprotinin
16% inhibition at 0.001 mM
leupeptin
38% inhibition at 0.001 mM
phenylmethylsulfonyl fluoride
almost complete inhibition at 10 mM
serpin A3
most potent serpin inhibitor, complete inhibition at 0.001 mM
-
serpin A5
about 40% inhibition at 0.001 mM
-
serpin C1
about 60% inhibition at 0.001 mM
-
serpin F2
about 35% inhibition at 0.001 mM
-
Zn2+
reversible inhibition. 5 mM ZnCl2 almost completely abolishes the enzyme activity. EDTA (final concentration of 50 mM) completely reverses the Zn2+ inhibition
additional information
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