3.4.21.48: cerevisin
This is an abbreviated version!
For detailed information about cerevisin, go to the full flat file.
Reaction
Hydrolysis of proteins with broad specificity, and of Bz-Arg-OEt Ac-Tyr-OEt. Does not hydrolyse peptide amides =
Synonyms
baker's yeast proteinase, baker's yeast proteinase B, brewer's yeast proteinase, EC 3.4.22.9, PRB1, Proteinase B, Proteinase YSCB, proteinase, yeast B, yeast proteinase B, yeast proteinase yscB
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General Information
General Information on EC 3.4.21.48 - cerevisin
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physiological function
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deletion of the rim101 gene involved in sporulation control results in upregulation of the PRB1 gene leading to higher levels of proteinase B activity. Increase in proteinase B activity results in severely compromised stability of some proteins such as Slt2p or Chs4p