3.4.21.36: pancreatic elastase

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For detailed information about pancreatic elastase, go to the full flat file.

Word Map on EC 3.4.21.36

3.4.21.36

porcine

exocrine

emphysema

fecal

elastin

pancreas

leukocyte

pulmonary

elastase-induced

elastases

instil

intratracheal

amylase

abdominal

alveolar

stool

aortic

aaa

elastolytic

aneurysm

lavage

bronchoalveolar

proteinases

emphysematous

airspace

hne

intercept

alpha-chymotrypsin

steatorrhea

1-antitrypsin

2-macroglobulin

1-proteinase

elastase-treated

analysis

elastase-mediated

elastatinal

maldigestion

isoamylase

cholangiopancreatography

alpha-1-proteinase

procarboxypeptidase

antiprotease

antielastase

intra-aortic

medicine

ovomucoid

non-pancreatic

pancreatoduodenectomy

carlsberg

desmosine

3.4.21.1

elastase-like

Reaction

Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-/- =

Synonyms

CELA1, CELA3A, CELA3B, chymotrypsin-like elastase, EC 3.4.21.11, EC 3.4.4.7, elastase, elastase 1, elastase-1, elaszym, ELT, FE1, pancreatic elastase, pancreatic elastase 3, pancreatic elastase 3B, pancreatic elastase I, pancreatic elastase-1, pancreatopeptidase E, PE 3B, PE-1, peptidase, pancreato-, E, PPE, PRT-201, serine elastase, type I pancreatic elastase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.36 pancreatic elastase

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Results	in table
3	Activating Compound
16	AA Sequence
6	Application
1	CAS Registry Number
1	Cloned(Commentary)
20	Crystallization (Commentary)
1641	Disease/ Diagnostics
1	Expression
5	General Stability
13	IC50 Value
103	Inhibitors
24	kcat/KM [mM/s]
27	Ki Value [mM]
39	KM Value [mM]
3	Metals/Ions
11	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
65	Organism
122	PDB ID
9	pH Optimum
3	pH Range
3	pH Stability
4	Posttranslational Modification
15	Purification (Commentary)
1	Reaction
1	Reaction Type
63	Reference
1	Renatured (Commentary)
46	Source Tissue
10	Specific Activity [micromol/min/mg]
1	Storage Stability
62	Substrates and Products (Substrate)
7	Subunits
51	Synonyms
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
30	Turnover Number [1/s]

Purification

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Purification on EC 3.4.21.36 - pancreatic elastase

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6 entries

ammonium sulfate precipitation and ion exchange chromatography

Mus musculus

697474

chromatofocusing and Superdex-75 gel filtration

Sus scrofa

P00772

669505

nickel-affinity chromatography

Homo sapiens

754151

two forms: EI and EII

Scyliorhinus canicula

36571