3.4.21.36: pancreatic elastase

This is an abbreviated version!
For detailed information about pancreatic elastase, go to the full flat file.

Word Map on EC 3.4.21.36

3.4.21.36

porcine

exocrine

emphysema

fecal

elastin

pancreas

leukocyte

pulmonary

elastase-induced

elastases

instil

intratracheal

amylase

abdominal

alveolar

stool

aortic

aaa

elastolytic

aneurysm

lavage

bronchoalveolar

proteinases

emphysematous

airspace

hne

intercept

alpha-chymotrypsin

steatorrhea

1-antitrypsin

2-macroglobulin

1-proteinase

elastase-treated

analysis

elastase-mediated

elastatinal

maldigestion

isoamylase

cholangiopancreatography

alpha-1-proteinase

procarboxypeptidase

antiprotease

antielastase

intra-aortic

medicine

ovomucoid

non-pancreatic

pancreatoduodenectomy

carlsberg

desmosine

3.4.21.1

elastase-like

Reaction

Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-/- =

Synonyms

CELA1, CELA3A, CELA3B, chymotrypsin-like elastase, EC 3.4.21.11, EC 3.4.4.7, elastase, elastase 1, elastase-1, elaszym, ELT, FE1, pancreatic elastase, pancreatic elastase 3, pancreatic elastase 3B, pancreatic elastase I, pancreatic elastase-1, pancreatopeptidase E, PE 3B, PE-1, peptidase, pancreato-, E, PPE, PRT-201, serine elastase, type I pancreatic elastase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.36 pancreatic elastase

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Results	in table
3	Activating Compound
16	AA Sequence
6	Application
1	CAS Registry Number
1	Cloned(Commentary)
20	Crystallization (Commentary)
1641	Disease/ Diagnostics
1	Expression
5	General Stability
13	IC50 Value
103	Inhibitors
24	kcat/KM [mM/s]
27	Ki Value [mM]
39	KM Value [mM]
3	Metals/Ions
11	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
65	Organism
122	PDB ID
9	pH Optimum
3	pH Range
3	pH Stability
4	Posttranslational Modification
15	Purification (Commentary)
1	Reaction
1	Reaction Type
63	Reference
1	Renatured (Commentary)
46	Source Tissue
10	Specific Activity [micromol/min/mg]
1	Storage Stability
62	Substrates and Products (Substrate)
7	Subunits
51	Synonyms
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
30	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.4.21.36 - pancreatic elastase

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0.00141

largamide A

Sus scrofa

710238

0.00294

largamide A methyl ester

Sus scrofa

710238

0.00053

largamide B

Sus scrofa

710238

0.00223

largamide B methyl ester

Sus scrofa

710238

0.00115

largamide C

Sus scrofa

710238

0.00216

largamide C methyl ester

Sus scrofa

710238

0.00012

lyngbyastatin 10

Sus scrofa

in Tris-HCl (pH 8.0)

709785

0.0000473

lyngbyastatin 7

Sus scrofa

in Tris-HCl (pH 8.0)

709785

0.000123

lyngbyastatin 8

Sus scrofa

in Tris-HCl (pH 8.0)

709785

0.00021

lyngbyastatin 9

Sus scrofa

in Tris-HCl (pH 8.0)

709785

0.00214

tiglicamide A

Sus scrofa

710238

0.00699

tiglicamide B

Sus scrofa

710238

0.00728

tiglicamide C

Sus scrofa

710238