3.4.21.113: pestivirus NS3 polyprotein peptidase

This is an abbreviated version, for detailed information about pestivirus NS3 polyprotein peptidase, go to the full flat file.

Reaction

Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites =

Synonyms

border disease virus NS3 endopeptidase, BVD NS3 endopeptidase, BVDV NS3 endopeptidase, classical swine fever virus NS3 endopeptidase, CSFV NS3 endopeptidase, flavivirus NS3 protease, nonstructural protein 3, nonstructural protein NS3, NS2B/NS3 protease, NS3, NS3 protease, NS3 protein, NS3 proteinase, NS3 serine protease, NS3-SP, NS3prohelx, P80pestivirus P80 protein, S31.001, viral diarrhea virus endopeptidase, WNV NS2B/NS3

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.113 pestivirus NS3 polyprotein peptidase