3.4.17.23: angiotensin-converting enzyme 2

This is an abbreviated version!
For detailed information about angiotensin-converting enzyme 2, go to the full flat file.

Word Map on EC 3.4.17.23

3.4.17.23

sars-cov-2

covid-19

coronavirus

spike

pandemic

renin-angiotensin

cardiovascular

hypertension

ras

pulmonary

outbreak

receptor-binding

distress

storm

comorbidities

tmprss2

blocker

endothelial

viruses

cardiac

december

wuhan

renin-angiotensin-aldosterone

angiotensin-1-7

renin

drug development

pharmacology

analysis

medicine

aceis

declared

diagnostics

covid

3clpro

angii

anosmia

pseudovirus

mers-cov

covid-19-related

counter-regulatory

contagious

anti-sars-cov-2

disease-2019

favipiravir

convalescent

corona

remdesivir

covid-19-associated

lockdown

camostat

pseudotyped

cough

hydroxychloroquine

s-proteins

furin

Reaction

Synonyms

ACE, ACE 2, ACE-2, ACE-related carboxypeptidase, ACE2, ACE2 homologue, ACEH, ACEII, Ang converting enzyme 2, angiotensin converting enzyme 2, angiotensin converting enzyme II, angiotensin converting enzyme-2, angiotensin II converting enzyme 2, angiotensin-converting enzyme, angiotensin-converting enzyme 2, angiotensin-converting enzyme homolog, angiotensin-converting enzyme homologue, angiotensin-converting enzyme type 2, angiotensin-converting enzyme-2, angiotensin-converting enzyme-like protein, angiotensin-converting enzyme-related carboxypeptidase, angiotensinase, hACE2, sACE2, soluble angiotensin converting enzyme 2, TMPRSS2

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.23 angiotensin-converting enzyme 2

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Results	in table
12	Activating Compound
54	AA Sequence
80	Application
1	CAS Registry Number
35	Cloned(Commentary)
10	Crystallization (Commentary)
8393	Disease/ Diagnostics
23	Expression
137	General Information
1	General Stability
16	IC50 Value
231	Inhibitors
53	Ki Value [mM]
10	KM Value [mM]
30	Localization
20	Metals/Ions
11	Molecular Weight [Da]
54	Natural Substrates/ Products (Substrates)
420	Organism
212	PDB ID
8	pH Optimum
1	pH Range
8	Posttranslational Modification
96	Protein Variants
15	Purification (Commentary)
3	Reaction
11	Reaction Type
258	Reference
298	Source Tissue
1	Specific Activity [micromol/min/mg]
223	Substrates and Products (Substrate)
7	Subunits
243	Synonyms
6	Temperature Optimum [°C]
1	Temperature Stability [°C]
9	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.4.17.23 - angiotensin-converting enzyme 2

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0.2

1,3,8-trihydroxy-6-methylanthraquinone

Homo sapiens

677603

0.096

1N-08795

Homo sapiens

681041

0.134

1N-26923

Homo sapiens

681041

0.116

1N-28616

Homo sapiens

681041

0.08 - 4

1S-91206

Homo sapiens

681041

0.179

4S-14713

Homo sapiens

681041

0.062

4S-16659

Homo sapiens

681041

0.005

Cu2+

Homo sapiens

679708

0.00001

DX600

Homo sapiens

IC50: 10 nM

668219

0.577

methylene blue

Homo sapiens

Q9BYF1

predicted value, pH not specified in the publication, temperature not specified in the publication

764799

0.000003

MLN 4760

2 entries

0.00000044

MLN-4760

Homo sapiens

i.e. (SS) 2-[(1)-carboxy-2-[3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl]ethylamino]-4-methyl-pentanoic acid, IC50: 0.44 nM

668219

0.15

Pro-Phe

Homo sapiens

IC50: 0.15 mM

668219

0.494

sennoside A

Homo sapiens

Q9BYF1

predicted value, pH not specified in the publication, temperature not specified in the publication

764799

0.27

varenicline

Homo sapiens

Q9BYF1

predicted value, pH not specified in the publication, temperature not specified in the publication

764799