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3.4.17.23: angiotensin-converting enzyme 2

This is an abbreviated version!
For detailed information about angiotensin-converting enzyme 2, go to the full flat file.

Word Map on EC 3.4.17.23

Reaction

angiotensin II
+
H2O
=
angiotensin-(1-7)
+
L-phenylalanine

Synonyms

ACE, ACE 2, ACE-2, ACE-related carboxypeptidase, ACE2, ACE2 homologue, ACEH, ACEII, Ang converting enzyme 2, angiotensin converting enzyme 2, angiotensin converting enzyme II, angiotensin converting enzyme-2, angiotensin II converting enzyme 2, angiotensin-converting enzyme, angiotensin-converting enzyme 2, angiotensin-converting enzyme homolog, angiotensin-converting enzyme homologue, angiotensin-converting enzyme type 2, angiotensin-converting enzyme-2, angiotensin-converting enzyme-like protein, angiotensin-converting enzyme-related carboxypeptidase, angiotensinase, hACE2, sACE2, soluble angiotensin converting enzyme 2, TMPRSS2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.23 angiotensin-converting enzyme 2

Purification

Purification on EC 3.4.17.23 - angiotensin-converting enzyme 2

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Ni3+-charged nitrilotriacetic acid-linked resin chromatography and and anti-Flag column chromatography
-
nickel-nitrilotriacetic acid agarose affinity chromatography
recombinant
recombinant enzyme
recombinant from CHO K1 cells
recombinant from Sf21 cells as mIgG-tagged protein
recombinant from Sf9 cells, to near homogeneity
recombinant truncated extracellular form of human ACE2 (residues 1–740)
recombinant wild-type and extracellular domain as FLAG-tagged proteins from Sf9 cells
soluble ACE2, residues 19 to 615, was expressed in Sf9 cells