3.2.1.87: capsular-polysaccharide endo-1,3-alpha-galactosidase
This is an abbreviated version!
For detailed information about capsular-polysaccharide endo-1,3-alpha-galactosidase, go to the full flat file.
Word Map on EC 3.2.1.87
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3.2.1.87
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bacteriophage
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o-antigens
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beta-helix
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endorhamnosidase
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octasaccharide
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homotrimeric
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carbapenem-resistant
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t7-like
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antivirulence
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endosialidase
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siphoviridae
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podoviridae
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beta-helices
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phage-encoded
- 3.2.1.87
- bacteriophage
-
o-antigens
-
beta-helix
-
endorhamnosidase
- octasaccharide
-
homotrimeric
-
carbapenem-resistant
-
t7-like
-
antivirulence
- endosialidase
- siphoviridae
- podoviridae
-
beta-helices
-
phage-encoded
Reaction
Synonyms
AM24 depolymerase, capsule depolymerase, depoKP36, Dpo48, galactohydrolase, capsular polysaccharide, gp50, K1E depolymerase, K1F depolymerase, K1H depolymerase, K30 depolymerase, K30 gp41, K30/K69 depolymerase, K30/K69dep, K5 depolymerase, K5dep, K8 depolymerase, K8dep, KP32gp37, KP32gp38, phage capsule depolymerase, polysaccharide depolymerase, tail fiber protein, tailspike protein
ECTree
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General Information
General Information on EC 3.2.1.87 - capsular-polysaccharide endo-1,3-alpha-galactosidase
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physiological function
Escherichia phage K1
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the enzyme actively degrades K1 capsule polysaccharide in vitro and sensitizes K1 bacteria to serum killing
physiological function
the enzyme decreases Klebsiella pneumoniae resistance to innate defense mechanisms and strongly affects the virulence of Klebsiella pneumoniae with the corresponding K3 and K21 capsular serotypes. The enzyme considerably increases the lifespan of Galleria mellonella larvae infected with Klebsiella pneumoniae in a time- and strain-dependent manner
physiological function
the enzyme degrades the bacterial surface exopolysaccharides of Actinetobacter baumannii types 208, 238, 420 and 1106
physiological function
the enzyme is able to infect and grow on either capsular types K30/K69 and K5 or K8 and K5 of Klebsiella strains. Bacterial killing is observed when incubated Klebsiella strains with phages but not with purified enzymes
physiological function
the enzyme is able to infect and grow on either capsular types K30/K69 and K5 or K8 and K5 of Klebsiella strains. Bacterial killing is observed when incubated Klebsiella strains with phages but not with purified enzymes
physiological function
the enzyme significantly inhibits Klebsiella-induced mortality of Galleria mellonella larvae in a time-dependent manner. The enzyme does not affect the action of antibiotics against Klebsiella pneumoniae strains