3.2.1.87: capsular-polysaccharide endo-1,3-alpha-galactosidase

This is an abbreviated version!
For detailed information about capsular-polysaccharide endo-1,3-alpha-galactosidase, go to the full flat file.

Reaction

Synonyms

AM24 depolymerase, capsule depolymerase, depoKP36, Dpo48, galactohydrolase, capsular polysaccharide, gp50, K1E depolymerase, K1F depolymerase, K1H depolymerase, K30 depolymerase, K30 gp41, K30/K69 depolymerase, K30/K69dep, K5 depolymerase, K5dep, K8 depolymerase, K8dep, KP32gp37, KP32gp38, phage capsule depolymerase, polysaccharide depolymerase, tail fiber protein, tailspike protein

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.87 capsular-polysaccharide endo-1,3-alpha-galactosidase

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Results	in table
6	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
6	General Information
3	General Stability
1	Inhibitors
1	Localization
1	Metals/Ions
7	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
12	Organism
4	pH Optimum
4	pH Range
2	pH Stability
1	pI Value
8	Purification (Commentary)
1	Reaction
1	Reaction Type
11	Reference
1	Specific Activity [micromol/min/mg]
13	Substrates and Products (Substrate)
12	Subunits
38	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Temperature Range [°C]
4	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 3.2.1.87 - capsular-polysaccharide endo-1,3-alpha-galactosidase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

bacterial surface polysaccharide + H2O

?

Acinetobacter phage IME-200

A0A0P0IJ73

-

751797

-

-

?

K1 capsule polysaccharide + H2O

?

Escherichia phage K1

-

-

750635

-

-

?

K30 capsule polysaccharide + H2O

?

Escherichia phage K30

-

-

750635

-

-

?

Klebsiella capsular polysaccharide + H2O

Klebsiella capsular monosaccharides

2 entries

Klebsiella pneumoniae capsule exopolysaccharides + H2O

?

Klebsiella phage KP36

K9L8R4

-

752325

-

-

?

[D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal]n + H2O

D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal

4 entries

additional information

?

-

5 entries

Klebsiella capsular polysaccharide + H2O

Klebsiella capsular monosaccharides

Klebsiella phage K5-2

A0A219YHC0

-

752225

-

-

?

Klebsiella capsular polysaccharide + H2O

Klebsiella capsular monosaccharides

Klebsiella phage K5-4

A0A219YHG0

-

752225

-

-

?

[D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal]n + H2O

D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal

Klebsiella aerogenes

-

capsular, polysaccharide produced by Aerobacter aerogenes, hydrolyzes the galactosyl-alpha-1,3-D-galactose linkages only in the complex substrate, bringing about depolymerization

136930

-

136930

?

[D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal]n + H2O

D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal

Klebsiella aerogenes

-

capsular, polysaccharide produced by Aerobacter aerogenes, hydrolyzes the galactosyl-alpha-1,3-D-galactose linkages only in the complex substrate, bringing about depolymerization

136931

-

136931

?

[D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal]n + H2O

D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal

Klebsiella aerogenes

-

capsular, polysaccharide produced by Aerobacter aerogenes, hydrolyses the galactosyl-alpha-1,3-D-galactose linkages only in the complex substrate, bringing about depolymerization, the enzyme is phage-induced and serves to degrade the capsular polysaccharide of the host

136930

-

136930

?

[D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal]n + H2O

D-Gal-(1-3)(D-GlcUA-(1-2))-alpha-D-Man-(1-3)-alpha-D-Gal

Klebsiella aerogenes

-

capsular, polysaccharide produced by Aerobacter aerogenes, hydrolyses the galactosyl-alpha-1,3-D-galactose linkages only in the complex substrate, bringing about depolymerization, the enzyme is phage-induced and serves to degrade the capsular polysaccharide of the host

136931

-

136931

?

additional information

?

-

Acinetobacter phage AM24

-

the enzyme interacts specifically with capsular polysaccharides of Acinetobacter baumannii B05

749767

-

-

?

additional information

?

-

Klebsiella phage KP32

D1L2X0

the enzymes have high specificity for the capsular serotypes K3 and K21

750649

-

-

?

additional information

?

-

Klebsiella phage KP32

D1L2X1

the enzymes have high specificity for the capsular serotypes K3 and K21

750649

-

-

?

additional information

?

-

Klebsiella phage KP32

-

the enzymes have high specificity for the capsular serotypes K3 and K21

750649

-

-

?

additional information

?

-

Klebsiella pneumoniae capsular serotype K2

-

virus K2 hydrolyses capsule of Aerobacter aerogenesis using glucane hydrolase splitting alpha1,3-bond between galactose residues

732740

-

-

?