3.2.1.48: sucrose alpha-glucosidase

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For detailed information about sucrose alpha-glucosidase, go to the full flat file.

Word Map on EC 3.2.1.48

3.2.1.48

border

brush

lactase

enterocytes

disaccharidase

caco-2

mucosal

crypt

jejunal

starch

maltase-glucoamylase

brush-border

glucoamylase

maltose

lactase-phlorizin

ileum

trehalase

microvillus

acarbose

basolateral

postprandial

dipeptidyl

villin

suckling

dipeptidylpeptidase

malabsorption

goblet

3.2.1.20

enterocyte-like

isomaltose

3.4.11.2

intestine-specific

carbohydrase

small-intestinal

aminopeptidase-n

postconfluent

crypt-villus

paneth

1-deoxynojirimycin

bloating

dextrin

agriculture

medicine

Reaction

= 2 D-glucose

Synonyms

alpha-glucosidase, glucosidase, sucrose alpha-, intestinal sucrase, isomaltase, More, PF0132, pro-SI, SI, sucrase, sucrase isomaltase, sucrase-invertase, sucrase-isomaltase, sucrase-isomaltase enzyme complex, sucrase/isomaltase, sucrose alpha-glucohydrolase, sucrose hydrolase, SUH

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.48 sucrose alpha-glucosidase

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Results	in table
6	Activating Compound
26	AA Sequence
4	Application
1	CAS Registry Number
19	Cloned(Commentary)
3	Crystallization (Commentary)
676	Disease/ Diagnostics
11	General Information
9	IC50 Value
62	Inhibitors
4	kcat/KM [mM/s]
5	Ki Value [mM]
57	KM Value [mM]
24	Localization
6	Metals/Ions
26	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
67	Organism
7	Pathway
4	PDB ID
18	pH Optimum
7	pH Range
1	pI Value
2	Posttranslational Modification
39	Protein Variants
18	Purification (Commentary)
3	Reaction
1	Reaction Type
66	Reference
36	Source Tissue
18	Specific Activity [micromol/min/mg]
3	Storage Stability
135	Substrates and Products (Substrate)
13	Subunits
40	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
3	Temperature Range [°C]
8	Temperature Stability [°C]
15	Turnover Number [1/s]

Purification

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Purification on EC 3.2.1.48 - sucrose alpha-glucosidase

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native enzyme

native enzyme from brush border 155fold by isolation from the microvillus membranes by papain, gel filtration and anion exchange chromatography

Mus musculus

707797

partially from intestinal mucosa by ammonium sulfate precipitation

Sus scrofa

664607

partially from jejunal brush border membrane by diffeential centrifugation and Mg2+ precipitation

Sus scrofa

665315

produced and purified in Escherichia coli RB791/pMalL

Bacillus subtilis

136522