3.1.6.4: N-acetylgalactosamine-6-sulfatase

This is an abbreviated version!
For detailed information about N-acetylgalactosamine-6-sulfatase, go to the full flat file.

Reaction

Synonyms

6-sulfatase, acetylgalactosamine 6-sulfatase, AtsA2, chondroitin sulfatase, chondroitinase, chondroitinsulfatase, galactose-6-sulfatase, galactose-6-sulfate sulfatase, GalNAc6S sulfatase, GALNS, N-acetylgalactosamine 6-sulfatase, N-acetylgalactosamine 6-sulphate sulphatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase, sulfatase, acetylgalactosamine 6-, sulfatase, chondroitin

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.6 Sulfuric-ester hydrolases

                3.1.6.4 N-acetylgalactosamine-6-sulfatase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
6	Activating Compound
802	AA Sequence
12	Application
2	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
778	Disease/ Diagnostics
1	Expression
7	General Information
2	General Stability
1	IC50 Value
40	Inhibitors
14	KM Value [mM]
5	Localization
23	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
45	Organism
2	Pathway
4	PDB ID
12	pH Optimum
2	pH Range
3	Posttranslational Modification
42	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
43	Reference
38	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
55	Substrates and Products (Substrate)
7	Subunits
31	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]

Cloned

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Cloned on EC 3.1.6.4 - N-acetylgalactosamine-6-sulfatase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Cloned (commentary) Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expressed in deficient fibroblasts

Homo sapiens

-

651453

expression in Chinese hamster ovary cells

Homo sapiens

-

135654

expression in Escherichia coli

Homo sapiens

P34059

752227

expression in Escherichiacoli BL21

Homo sapiens

P34059

730183

expression in MCF-7 cells. Following overexpression of the enzyme, total sulfated glycosaminoglycans, chondroitin 4-sulfate, and chondroitin sulfates decline significantly

Homo sapiens

P34059

680928

expression in Pichia pastoris

Homo sapiens

P34059

752199

overexpression in chinese hamster ovary cells

Homo sapiens

-

681958

recombinant enzyme expression in Escherichia coli strain BL21 in both soluble and inclusion bodies fractions, rGALNS amounts in inclusion bodies fraction are up to 17fold higher than those observed in the soluble fraction, method optimization, effect of aeration and agitation at bench scale, detailed overview

Homo sapiens

P34059

715797

the GALNS gene is located on chromosome 16q24.3, DNA and amino acid sequence determination and analysis of wild-type and mutant genes

Homo sapiens

-

666376