3.1.11.6: exodeoxyribonuclease VII

This is an abbreviated version!
For detailed information about exodeoxyribonuclease VII, go to the full flat file.

Word Map on EC 3.1.11.6

3.1.11.6

single-stranded

nucleases

reca

sbccd

methyl-directed

analysis

recbcd

Reaction

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates =

Synonyms

E. coli exonuclease VII, endodeoxyribonuclease VII, Escherichia coli exonuclease VII, exonuclease VII, ExoVII, nuclease, exodeoxyribo-, VII, RecBCD, XseA, XseB

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.11 Exodeoxyribonucleases producing 5′-phosphomonoesters

3.1.11.6 exodeoxyribonuclease VII

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Results	in table
6	Activating Compound
66501	AA Sequence
11	Application
1	CAS Registry Number
5	Cloned(Commentary)
1	Crystallization (Commentary)
11	General Information
1	General Stability
7	Inhibitors
2	Localization
4	Metals/Ions
6	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
76	Organism
6	PDB ID
2	pH Optimum
2	pH Stability
26	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
36	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
66	Substrates and Products (Substrate)
6	Subunits
30	Synonyms
2	Temperature Optimum [°C]
4	Temperature Stability [°C]

Subunits

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Subunits on EC 3.1.11.6 - exodeoxyribonuclease VII

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dimer

Escherichia coli

P04994; P0A8G9

exonuclease VII of Escherichia coli is composed of two different subunits, the large subunit, XseA, and the small subunit, XseB

751292

heterodimer

Escherichia coli

P04994; P0A8G9

enzyme ExoVII consists of two subunits that are encoded by xseA and xseB. Gene xseA encodes the catalytically active subunit, while xseB encodes for a smaller subunit which is likely to regulate the activity of ExoVII

751755

pentamer

2 entries

additional information

Thermotoga maritima

stoichiometry of small to large subunits regulates ExoVII activity

700496