2.1.1.44: L-histidine Nalpha-methyltransferase
This is an abbreviated version!
For detailed information about L-histidine Nalpha-methyltransferase, go to the full flat file.
Reaction
3 S-adenosyl-L-methionine
+
=
3 S-adenosyl-L-homocysteine
+
Synonyms
dimethylhistidine methyltransferase, EgtD, histidine-alpha-N-methyltransferase, methyltransferase, histidine Nalpha-
ECTree
KCat KM Value
KCat KM Value on EC 2.1.1.44 - L-histidine Nalpha-methyltransferase
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0.0024 - 0.1
L-phenylalanine
0.0011 - 0.017
L-tyrosine
17
Nalpha,Nalpha-dimethyl-L-histidine
wild-type, pH 8.0, 26°C
13
Nalpha-methyl-L-histidine
wild-type, pH 8.0, 26°C
0.0019
L-histidine
mutant M252A/E285A, pH 8.0, 26°C
0.04
L-histidine
mutant E285A, pH 8.0, 26°C
5.3
L-histidine
wild-type, pH 8.0, 26°C
0.0024
L-phenylalanine
wild-type, pH 8.0, 26°C
0.1
L-phenylalanine
mutant M252A/E285A, pH 8.0, 26°C
0.002
L-tryptophan
wild-type, pH 8.0, 26°C
0.4
L-tryptophan
mutant E285A, pH 8.0, 26°C
5.5
L-tryptophan
mutant M252A/E285A, pH 8.0, 26°C
0.0011
L-tyrosine
wild-type, pH 8.0, 26°C
0.017
L-tyrosine
mutant M252A/E285A, pH 8.0, 26°C