2.1.1.44: L-histidine Nalpha-methyltransferase

This is an abbreviated version!
For detailed information about L-histidine Nalpha-methyltransferase, go to the full flat file.

3 S-adenosyl-L-methionine +

= 3 S-adenosyl-L-homocysteine +

dimethylhistidine methyltransferase, EgtD, histidine-alpha-N-methyltransferase, methyltransferase, histidine Nalpha-

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Results	in table
5087	AA Sequence
1	CAS Registry Number
1	Crystallization (Commentary)
14	Inhibitors
12	kcat/KM [mM/s]
1	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
3	Organism
4	Pathway
30	PDB ID
3	pH Optimum
4	Protein Variants
1	Purification (Commentary)
4	Reaction
1	Reaction Type
3	Reference
1	Specific Activity [micromol/min/mg]
19	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
4	Turnover Number [1/s]

Reaction on EC 2.1.1.44 - L-histidine Nalpha-methyltransferase

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3 S-adenosyl-L-methionine + L-histidine = 3 S-adenosyl-L-homocysteine + hercynine

overall reaction

S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + Nalpha-methyl-L-histidine

(1a)

S-adenosyl-L-methionine + Nalpha,Nalpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + hercynine

(1c)

S-adenosyl-L-methionine + Nalpha-methyl-L-histidine = S-adenosyl-L-homocysteine + Nalpha,Nalpha-dimethyl-L-histidine

(1b)