2.1.1.44: L-histidine Nalpha-methyltransferase

This is an abbreviated version!
For detailed information about L-histidine Nalpha-methyltransferase, go to the full flat file.

Reaction

3 S-adenosyl-L-methionine +

Synonyms

dimethylhistidine methyltransferase, EgtD, histidine-alpha-N-methyltransferase, methyltransferase, histidine Nalpha-

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.44 L-histidine Nalpha-methyltransferase

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Results	in table
5087	AA Sequence
1	CAS Registry Number
1	Crystallization (Commentary)
14	Inhibitors
12	kcat/KM [mM/s]
1	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
3	Organism
4	Pathway
30	PDB ID
3	pH Optimum
4	Protein Variants
1	Purification (Commentary)
4	Reaction
1	Reaction Type
3	Reference
1	Specific Activity [micromol/min/mg]
19	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
4	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.44 - L-histidine Nalpha-methyltransferase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

3 S-adenosyl-L-methionine + L-histidine

3 S-adenosyl-L-homocysteine + hercynine

2 entries

S-adenosyl-L-methionine + histidine

S-adenosyl-L-homocysteine + Nalpha-methylhistidine

Neurospora crassa

-

-

441301

-

-

?

S-adenosyl-L-methionine + L-histidine

S-adenosyl-L-homocysteine + Nalpha-methyl-L-histidine

2 entries

S-adenosyl-L-methionine + methylhistidine

S-adenosyl-L-homocysteine + Nalpha,Nalpha-dimethyl-L-histidine

Neurospora crassa

-

-

441301

-

-

?

S-adenosyl-L-methionine + Nalpha,Nalpha-dimethyl-L-histidine

S-adenosyl-L-homocysteine + hercynine

2 entries

S-adenosyl-L-methionine + Nalpha,Nalpha-dimethyl-L-histidine

S-adenosyl-L-homocysteine + Nalpha,Nalpha,Nalpha-trimethyl-L-histidine

Neurospora crassa

-

-

441301

-

441301

?

S-adenosyl-L-methionine + Nalpha-methyl-L-histidine

S-adenosyl-L-homocysteine + Nalpha,Nalpha-dimethyl-L-histidine

2 entries

3 S-adenosyl-L-methionine + L-histidine

3 S-adenosyl-L-homocysteine + hercynine

Mycolicibacterium smegmatis

A0R5M8

-

756445

-

-

?

3 S-adenosyl-L-methionine + L-histidine

3 S-adenosyl-L-homocysteine + hercynine

Mycolicibacterium smegmatis ATCC 700084

A0R5M8

-

756445

-

-

?

S-adenosyl-L-methionine + L-histidine

S-adenosyl-L-homocysteine + Nalpha-methyl-L-histidine

Mycolicibacterium smegmatis

A0R5M8

-

756445

-

-

?

S-adenosyl-L-methionine + L-histidine

S-adenosyl-L-homocysteine + Nalpha-methyl-L-histidine

Mycolicibacterium smegmatis ATCC 700084

A0R5M8

-

756445

-

-

?

S-adenosyl-L-methionine + Nalpha,Nalpha-dimethyl-L-histidine

S-adenosyl-L-homocysteine + hercynine

Mycolicibacterium smegmatis

A0R5M8

-

756445

-

-

?

S-adenosyl-L-methionine + Nalpha,Nalpha-dimethyl-L-histidine

S-adenosyl-L-homocysteine + hercynine

Mycolicibacterium smegmatis ATCC 700084

A0R5M8

-

756445

-

-

?

S-adenosyl-L-methionine + Nalpha-methyl-L-histidine

S-adenosyl-L-homocysteine + Nalpha,Nalpha-dimethyl-L-histidine

Mycolicibacterium smegmatis

A0R5M8

-

756445

-

-

?

S-adenosyl-L-methionine + Nalpha-methyl-L-histidine

S-adenosyl-L-homocysteine + Nalpha,Nalpha-dimethyl-L-histidine

Mycolicibacterium smegmatis ATCC 700084

A0R5M8

-

756445

-

-

?