1.1.1.29: glycerate dehydrogenase

This is an abbreviated version, for detailed information about glycerate dehydrogenase, go to the full flat file.

Reaction

D-glycerate
+
NAD+
=
Hydroxypyruvate
+
NADH
+
H+

Synonyms

D-glycerate dehydrogenase, dehydrogenase, glycerate, GDH, glyoxalate reductase/hydroxypyruvate reductase, glyoxylate reductase, GR/HPR, GRHPR, HPR, HPR1, hydroxypyruvate dehydrogenase, hydroxypyruvate reductase, hydroxypyruvate reductase 1, NADH-dependent hydroxypyruvate reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.29 glycerate dehydrogenase

General Information

General Information on EC 1.1.1.29 - glycerate dehydrogenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
enzyme knockdown leads to an inhibition of ascorbic acid uptake
physiological function
-
rates of photosynthesis under photorespiratory conditions are slightly reduced in mutant plants lacking isoform hpr1 expression or additionally lacking both of the peroxisomal malate dehydrogenase genes, mutant pmdh1pmdh2hpr1. The CO2 compensation points increase under photorespiratory conditions in both mutants. The increase in CO2 compensation points in the hpr1 and pmdh1pmdh2hpr1 plants is not associated with changes in mitochondrial respiration but with an increase in the non-respiratory CO2 released per Rubisco oxygenation reaction