EC Number |
Protein Variants |
Reference |
---|
4.4.1.30 | C116S |
in vitro assay,11% of wild-type activity |
-, 731875 |
4.4.1.30 | C137S |
in vitro assay, 11% of wild-type activity |
731875 |
4.4.1.30 | D163A |
lyase activity is less than 5% compared to wild-type enzyme |
732151 |
4.4.1.30 | D163V |
lyase activity is less than 5% compared to wild-type enzyme |
732151 |
4.4.1.30 | D63N |
lyase activity is about 70% compared to wild-type enzyme |
732151 |
4.4.1.30 | E111Q |
lyase activity is about 75% compared to wild-type enzyme |
-, 732151 |
4.4.1.30 | H33F |
in vitro assay, 14% of wild-type activity |
-, 731875 |
4.4.1.30 | K87M |
lyase activity is about 70% compared to wild-type enzyme |
732151 |
4.4.1.30 | M118A |
lyase activity is about 25% compared to wild-type enzyme |
732151 |
4.4.1.30 | more |
chemical modification of arginine, histidine, tryptophan, lysine and amino acid carboxyl groups of isoform CpcT1 decreases activity to 30-84% of wild-type |
-, 731875 |