EC Number   |
Protein Variants |
Reference |
|---|
   4.2.2.17 | A257S |
mutation of residue in central tunnel, no significant change of temperature stability |
748014 |
| 4.2.2.17 | A257S/G281S G281S |
mutation of residues in central tunnel, increase in temperature stability by 3 degrees |
748014 |
| 4.2.2.17 | A257T |
mutation of residue in central tunnel, 2.8 degrees decrease of temperature stability |
748014 |
| 4.2.2.17 | D183A |
complete loss of activity |
-, 747956 |
| 4.2.2.17 | D183N |
complete loss of activity |
-, 747956 |
| 4.2.2.17 | E194A |
complete loss of activity |
-, 747956 |
| 4.2.2.17 | E194N |
complete loss of activity |
-, 747956 |
| 4.2.2.17 | G121A/T122L |
148.7% of wild-type activity, about 4.5 degrees increase in temperature stability |
748014 |
| 4.2.2.17 | G236S/G281S/A257S/T313S/A314S |
140.5% of wild-type activity, increase in temperature stability by 3.5 degrees |
748014 |
| 4.2.2.17 | G281S |
mutation of residue in central tunnel, 76% of wild-type activity, increase in temperature stability by 3 degrees |
748014 |
