EC Number   |
Protein Variants |
Reference |
|---|
   3.4.11.1 | D347E |
oligonucleotide site-directed mutagenesis, formation of a more complex structure compared to the wild-type enzyme, nearly catalytically inactive with dipeptide substrates |
651119 |
| 3.4.11.1 | D347E |
site-directed mutagenesis, inactive mutant |
665076 |
| 3.4.11.1 | D347G |
oligonucleotide site-directed mutagenesis, formation of a stable hexamer corresponding to the wild-type enzyme, nearly catalytically inactive with dipeptide substrates |
651119 |
| 3.4.11.1 | D347I |
oligonucleotide site-directed mutagenesis, no formation of stable hexamer, inactive mutant |
651119 |
| 3.4.11.1 | D347N |
mutation leads to inactivation of peptidase activity but does not have an impact on chaperone activity |
732053 |
| 3.4.11.1 | D347N |
oligonucleotide site-directed mutagenesis, no formation of stable hexamer, inactive mutant |
651119 |
| 3.4.11.1 | D347R |
inactive mutant with disrupted hexameric structure has increased chaperone activity |
732053 |
| 3.4.11.1 | D347R |
oligonucleotide site-directed mutagenesis, formation of a stable hexamer corresponding to the wild-type enzyme, reduced catalytic activity with dipeptide substrates compared to the wild-type |
651119 |
| 3.4.11.1 | D347R |
site-directed mutagenesis, reduced activity |
665076 |
| 3.4.11.1 | D347S |
oligonucleotide site-directed mutagenesis, no formation of stable hexamer, inactive mutant |
651119 |
