EC Number   |
Protein Variants |
Reference |
|---|
    3.2.2.1 | C248P |
mutant shows decreased kcat value compared to the wild type enzyme using guanosine as substrate |
698781 |
| 3.2.2.1 | C253A |
kcat/KM values for the hydrolysis of inosine, adenosine and guanosine are reduced by a factor of about 120fold compared to the wild-tpe enzyme |
752135 |
| 3.2.2.1 | C42A |
the kcat/KM values for the hydrolysis of inosine, adenosine, and guanosine are reduced by a factor of about 14-, 22-, and 10fold, respectively, compared to the wild-type enzyme |
752135 |
| 3.2.2.1 | D250A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
-, 732656 |
| 3.2.2.1 | D252A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
-, 732656 |
| 3.2.2.1 | D253P |
mutant shows increased kcat value compared to the wild type enzyme using guanosine as substrate |
698781 |
| 3.2.2.1 | D25A |
site-directed mutagenesis, inactive mutant |
732656 |
| 3.2.2.1 | D8A |
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme |
732656 |
| 3.2.2.1 | E247A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
732656 |
| 3.2.2.1 | E249P |
mutant shows decreased kcat value compared to the wild type enzyme using guanosine as substrate |
698781 |
