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Results 1 - 10 of 47 > >>
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227A/S287G/A328W/E441D the mutant shows 1730fold improved (-)-cocaine-hydrolyzing activity compared to the wild type enzyme 716278
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227A/S287G/A328W/Y332G the mutant has a 2020fold improved catalytic efficiency against (-)-cocaine compared to the wild type enzyme 714226
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227A/S287G/A328W/Y332G/E441D the mutant shows 1390fold improved (-)-cocaine-hydrolyzing activity compared to the wild type enzyme 716278
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227A/S287G/A328W/Y332G/F329V the mutant has a 121fold improved catalytic efficiency against (-)-cocaine compared to the wild type enzyme 714226
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227I/S287G/A328W/Y332G the mutant has a 1170fold improved catalytic efficiency against (-)-cocaine compared to the wild type enzyme 714226
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227L/S287G/A328W/Y332G the mutant has a 1130fold improved catalytic efficiency against (-)-cocaine compared to the wild type enzyme 714226
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/F227V/S287G/A328W/Y332G the mutant has a 1490fold improved catalytic efficiency against (-)-cocaine compared to the wild type enzyme 714226
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/S287G/A328W/Y332G the mutant has a 1080fold improved catalytic efficiency against (-)-cocaine compared to the wild type enzyme 714226
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/S287G/A328W/Y332G the mutant shows 1080fold improved (-)-cocaine-hydrolyzing activity compared to the wild type enzyme 716278
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.84A199S/S287G/A328W/Y332G the mutant shows high activity towards (-)-cocaine with about 1080fold (un-fused) and 100fold (when fused with human serum albumin) improved catalytic efficiency compared to the wild type enzyme and also leads to a decrease in catalytic efficiency with acetylthiocholine and butyrylthiocholine 714702
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