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EC Number
Protein Variants
Commentary
Reference
2.8.3.8
E294A
the mutant shows severely reduced catalytic efficiency compared to the wild type enzyme
-
,
721675
2.8.3.8
E435A
insoluble mutant
-
,
721675
2.8.3.8
E435D
the mutant shows almost wild type activity
721675
2.8.3.8
E435Q
insoluble mutant
-
,
721675
2.8.3.8
R228E
the mutant has a specific defect in its ability to bind both carboxylate substrates succinyl-CoA and acetyl-CoA and does not use 4-aminobutyrate as substrate
-
,
721675
2.8.3.8
S71A
the mutant shows severely reduced catalytic efficiency compared to the wild type enzyme
-
,
721675
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