EC Number   |
Protein Variants |
Reference |
|---|
   2.7.11.30 | more |
activin receptor-like kinase 6 Booroola mutation enhances suppressive effects of bone morphogenetic protein 2, BMP2, BMP4, BMP6 and growth and differentiation factor-9 on FSH release from ovine primary pituitary cell cultures |
693381 |
| 2.7.11.30 | more |
ALK1 mutations cause hereditary hemorrhagic telangiectasia in association with pulmonary arterial hypertension, PAH, in patients, determination of polymorphisms in Japanese pulmonary arterial hypertension patients, phenotypes, overview |
691833 |
| 2.7.11.30 | more |
conferring of responsiveness to GDF-9-mediated stimulation of ALK5 and Smad3 phosphorylation in normally unresponsive COS-7 cells by overexpression of the three proteins, no responsiveness by co-expression with BMPRII receptor, expression of GDF-9 in a CAGA-luciferase reporter construct in P19 cells reveals that GDF-9 binds to BMP-activated type II receptors but its downstream actions are mediated by the type I receptor ALK5, overview, expression of ALK5 siRNA inhibits GDF-9-induced stimulation in granulosa cells |
666359 |
| 2.7.11.30 | T194D |
constitutive active ALK7 mutant |
665532 |
| 2.7.11.30 | Q201D |
constitutively active ALK1 mutant |
665699 |
| 2.7.11.30 | T204D |
constitutively active ALK5 mutant |
664088 |
| 2.7.11.30 | more |
construction of a truncated dominant negative ALK4 mutant |
665487 |
| 2.7.11.30 | more |
construction of a truncated mutant ALK7 |
664282 |
| 2.7.11.30 | more |
expression of HA-tagged wild-type ALK7 in rat FaO hepatoma cells and transiently of HA-tagged ALK mutant T194D in human Hep3B hepatoma cells using the adenovirus infection method, expression leads in both cases to an apoptosis-positive phenotype, expression of inactive ALK7 mutant K222R dos not cause an altered phenotype |
665532 |
| 2.7.11.30 | more |
functional co-expression of TGF-beta and the soluble intracellular domain of the TGF-beta type I receptor in murine mammary gland epithelial cells induces transdifferentiation of epithelial cells to mesenchymal cells, overview |
663984 |
