EC Number   |
Protein Variants |
Reference |
|---|
   2.4.1.69 | C35T |
the mutation is a polymorphism in the Chinese population and does not affect its mRNA transcription, but can slightly decrease the activity of human alpha-(1,2)-fucosyltransferase in vitro |
723789 |
| 2.4.1.69 | F280S |
missense polymorphism, almost inactive enzyme, responsible for some non-secretor cases |
657849 |
| 2.4.1.69 | G247S |
missense polymorphism, almost inactive enzyme, responsible for some non-secretor case |
657849 |
| 2.4.1.69 | H152A |
Km increased compared to wild-type using substrate lactulose and substrate GDP-fucose |
690942 |
| 2.4.1.69 | H152R |
Km increased compared to wild-type using substrate lactulose and substrate GDP-fucose |
690942 |
| 2.4.1.69 | I129F |
most frequent nonsense mutation of FUT2 in populations of Asian ancestry |
705849 |
| 2.4.1.69 | L101F |
spontaneous missense mutation frequent in Asian populations |
703927 |
| 2.4.1.69 | more |
bp428 G>A is a spontaneous nonsense mutation, 739G > A substitution does not inactivate the enzyme |
703927 |
| 2.4.1.69 | more |
fusion protein with a C-terminal HPC4-epitope tag is created |
703885 |
| 2.4.1.69 | more |
human bone marrow endothelial cells (HBMEC) FUT1-siRNA-transfectants display impaired in vitro angiogenesis when cultivated on extracellular matrix and in spheroid assays |
693324 |
