EC Number   |
Protein Variants |
Reference |
|---|
    2.4.1.129 | more |
construction of DELTA pbp2A deletion mutants. Domain architecture of PBP1a, TP active site motifs and mapped mutations in gene pbp1a in DELTAmltG suppressor strains. DELTApbp2A/DELTAmltG mutant phenotype, overview |
-, 759785 |
| 2.4.1.129 | more |
construction of DELTA pbp2B deletion mutants. Mutations in spd_1346 (mltG) suppress a DELTApbp2b deletion mutation. DELTApbp2B/DELTAmltG mutant phenotype, overview |
-, 759785 |
| 2.4.1.129 | more |
construction of the MtgA (D68-R269) mutant lacking the transmembrane segment |
758865 |
| 2.4.1.129 | more |
introduction of wild-type and mutant SgtBs in a wild-type Staphylococcus aureus strain and in an ltaS mutant strain (ANG2135) deficient in lipoteichoic acid (LTA). Growth and cell morphology of wild-type and mutant strains. Introduction of SgtB or MazE in the respective suppressor strain results in growth arrest. Inactivation of MazE or SgtB is sufficient to allow Staphylococcus aureus to grow in the absence of LTA. Inactivation of SgtB leading to an increase in peptidoglycan cross-linking in an LTA-negative Staphylococcus aureus strain. Increased resistance of the sgtB mutant to oxacillin |
759431 |
| 2.4.1.129 | E100Q |
mutant of the soluble form of Staphylococcus aureus MGT devoid of its membrane anchor, called SauH6-MGT. glycosyltransferase activity of the mutant is reduced 500fold compared to the wild type |
674268 |
| 2.4.1.129 | S116A |
mutant shows 10fold reduced activity compared to the wild type enzyme |
701437 |
| 2.4.1.129 | K124A |
mutant shows 5fold reduced activity compared to the wild type enzyme |
701437 |
| 2.4.1.129 | R132A |
mutant with barely detectable activity (about 3% of wild type) |
701437 |
| 2.4.1.129 | F237A |
mutant with completely abolished activity |
704438 |
| 2.4.1.129 | H240A |
mutant with completely abolished activity |
704438 |
