EC Number |
Protein Variants |
Reference |
---|
2.4.1.129 | E233Q |
mutation inactivates the transglycosylase domain |
659960 |
2.4.1.129 | E100Q |
mutant of the soluble form of Staphylococcus aureus MGT devoid of its membrane anchor, called SauH6-MGT. glycosyltransferase activity of the mutant is reduced 500fold compared to the wild type |
674268 |
2.4.1.129 | E83A |
mutant with undetectable activity |
701437 |
2.4.1.129 | K124A |
mutant shows 5fold reduced activity compared to the wild type enzyme |
701437 |
2.4.1.129 | K137A |
mutant with undetectable activity |
701437 |
2.4.1.129 | Q121A |
mutant with undetectable activity |
701437 |
2.4.1.129 | R132A |
mutant with barely detectable activity (about 3% of wild type) |
701437 |
2.4.1.129 | S116A |
mutant shows 10fold reduced activity compared to the wild type enzyme |
701437 |
2.4.1.129 | N526K |
the mutant shows decreased susceptibility toward ampicillin and amoxicillin |
703388 |
2.4.1.129 | D234N |
the mutant shows 14% of wild type activity |
704438 |