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Results 1 - 5 of 5
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.359D329A the mutant shows strongly decreased activity compared to the wild type enzyme 754092
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.359H2113K methyltransferase-deficient mutant 720843
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.359R1625C the mutation results in a complete loss of histone H3 lysine 36 trimethylation activity. The mutant shows unchanged thermal stability as compared with the wild type protein but diminished binding to the histone H3 tail 754138
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.359R195C the mutation results in a complete loss of histone H3 lysine 36 trimethylation activity but does not affect dimethylated histone H3 lysine 36 754138
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.359R2510H the mutation does not result in an observable defect in enzymatic function 754138
Results 1 - 5 of 5
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