EC Number   |
Protein Variants |
Reference |
|---|
    6.2.1.13 | H533K |
the variant retains about 10% activity compared to wild type enzyme |
744911 |
| 6.2.1.13 | H533N |
the variant retains about 5% activity compared to wild type enzyme |
744911 |
| 6.2.1.13 | H533Q |
the variant retains about 5% activity compared to wild type enzyme |
744911 |
| 6.2.1.13 | H533R |
the variant retains about 10% activity compared to wild type enzyme |
744911 |
| 6.2.1.13 | H533R |
the variant retains less than 25% activity compared to wild type enzyme |
744911 |
| 6.2.1.13 | H71betaA |
site-directed mutagenesis, comparison of the wild-type CD spectrum with the mutant CD spectrum, structure and reaction kinetics, overview. Inactive mutant, which is impaired in phosphorylation of the beta subunit |
693061 |
| 6.2.1.13 | more |
gradual ACS gene silencing (49-93%) significantly decreases the acetate flux without affecting the levels of glycolytic metabolites and ATP in trophozoites. Amoebae lacking ACS activity are unable to reestablish the acetyl-CoA/CoA ratio after an oxidative stress challenge |
744414 |
