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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.70T183A 1200fold decrease in kcat/Km compared to wild-type value 678296
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.70V168A Tm is 1.7°C lower than the Tm-value of wild-type enzyme. kcat/Km is 5.5fold lower than wild-type value 680902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.70Y143A mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation completely disrupts dimerization 678330
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