EC Number |
Protein Variants |
Reference |
---|
3.1.1.53 | S332A |
the mutation does not influence the activity of the enzyme significantly |
750708 |
3.1.1.53 | S40A |
catalytically inactive, active site residue, retained lectin activity |
700987 |
3.1.1.53 | S57T |
loss of esterase activity |
673893 |
3.1.1.53 | T132A |
complete loss of activity |
750708 |
3.1.1.53 | T132A |
the mutation abolishes the enzymatic activity |
750708 |
3.1.1.53 | T294A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type NanS |
716859 |
3.1.1.53 | T294S |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type NanS |
716859 |
3.1.1.53 | V459I |
naturally occuring mutation |
730718 |
3.1.1.53 | Y184A |
decreased ligand binding affinity |
700987 |