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Information on EC 3.1.1.53 - sialate O-acetylesterase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.53 sialate O-acetylesterase
IUBMB Comments
Acts on free and glycosidically bound N-acetyl- or N-glycoloyl-neuraminic acid; acts mainly on the 4-O- and 9-O-acetyl groups. Also acts on some other O-acetyl esters, both cyclic and acyclic compounds, which are not sialic acids.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
4-SOAE, 9(4)-O-acetylesterase, 9-O-acetyl N-acetylneuraminic acid esterase, 9-O-acetyl sialic acid esterase, 9-O-acetylsialic acid esterase, 9-SOAE, AXE, BCoVHE, CSE, cytosolic sialate:O-acetylesterase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate
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acts on free and glycosidically bound N-acetyl- or N-glycoloyl-neuraminic acid, acts mainly on the 4-O- and 9-O-acetyl groups. Also acts on some other O-acetyl esters, both cyclic and acyclic compounds, which are not sialic acids
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