EC Number   |
Protein Variants |
Reference |
|---|
   2.3.1.286 | Y117F |
site-directed mutagenesis, mutation of the conserved catalytic amino acid does not alter YjaB-dependent acetylation compared to wild-type |
757557 |
| 2.3.1.286 | E78A |
site-directed mutagenesis, mutation of the conserved catalytic amino acid prevents PhnO-dependent acetylation |
757557 |
| 2.3.1.286 | Y128A |
site-directed mutagenesis, mutation of the conserved catalytic amino acid prevents PhnO-dependent acetylation |
757557 |
| 2.3.1.286 | Y115A |
site-directed mutagenesis, mutation of the conserved catalytic amino acid prevents YiaC-dependent acetylation. Mutant YiaC Y115A is unable to inhibit cell migration in contrast to the wild-type enzyme |
757557 |
| 2.3.1.286 | F70A |
site-directed mutagenesis, mutation of the conserved catalytic amino acid reduces YiaC-dependent acetylation compared to wild-type. Overexpression of YiaC YF70A inhibits cell migration similarly to overexpression of wild-type YiaC |
757557 |
| 2.3.1.286 | Y117A |
site-directed mutagenesis, mutation of the conserved catalytic amino acid reduces YjaB-dependent acetylation compared to wild-type |
757557 |
| 2.3.1.286 | H135A |
the kcat/Km profile for the mutant exhibits no pH dependence over the range tested (pH 5.4-9.4), with kcat/Km values 2 orders of magnitude lower than wild type at high pH values |
749880 |
| 2.3.1.286 | I117V |
the mutant is nearly as active as the wild type protein (about 65% activity) |
751549 |
| 2.3.1.286 | I117F |
the mutant is nearly as active as the wild type protein (about 75% activity) |
751549 |
| 2.3.1.286 | D118N |
the mutant retains approximately 13% of the activity of the wild type protein |
751549 |
