EC Number   |
Protein Variants |
Reference |
|---|
    1.14.14.17 | F223A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme, the F223A mutant no longer accepts (3S)2,3-oxidosqualene as a substrate |
684828 |
| 1.14.14.17 | F228A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
684828 |
| 1.14.14.17 | F287A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
684828 |
| 1.14.14.17 | F305A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
684828 |
| 1.14.14.17 | F35A/S37A/L65A/I69A |
mutant displays blunted cholesterol regulation |
745376 |
| 1.14.14.17 | F375A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
684828 |
| 1.14.14.17 | F402L |
the point mutation causes terbinafine resistance |
715725 |
| 1.14.14.17 | F420L |
the point mutation causes terbinafine resistance |
715725 |
| 1.14.14.17 | F430S |
the point mutation causes terbinafine resistance |
715725 |
| 1.14.14.17 | F476A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
684828 |
