EC Number   |
Protein Variants |
Reference |
|---|
    1.1.1.248 | L266S |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689571 |
| 1.1.1.248 | L266V |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689571 |
| 1.1.1.248 | M271A |
decrease in kcat |
698937 |
| 1.1.1.248 | M271A |
increase in Km |
698937 |
| 1.1.1.248 | M271A |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |
| 1.1.1.248 | M271T |
site-directed mutagenesis, inactive mutant |
689571 |
| 1.1.1.248 | more |
specific virus-induced gene silencing as a functional genomics tool to investigate the regulation of morphine biosynthesis via a systematic reduction in enzyme levels responsible for the final six steps in the pathway, overview. Reduced SalR protein levels correlate with lower morphine levels and a substantial increase in the accumulation of salutaridine |
720707 |
| 1.1.1.248 | N152A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689571 |
| 1.1.1.248 | N272A |
increase in Km, decrease in kcat |
698937 |
| 1.1.1.248 | N272A |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |
