EC Number |
Protein Variants |
Reference |
---|
1.1.1.248 | K186V |
moderate effects on substrate affinity, exhibits a turnover number similar to that of the wild-type |
698937 |
1.1.1.248 | K186V |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |
1.1.1.248 | K240E |
site-directed mutagenesis, inactive mutant |
689571 |
1.1.1.248 | L185A |
increase in Km, decrease in kcat |
698937 |
1.1.1.248 | L185A |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |
1.1.1.248 | L185S |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |
1.1.1.248 | L185V |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |
1.1.1.248 | L266A |
decrease in kcat |
698937 |
1.1.1.248 | L266A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689571 |
1.1.1.248 | L266A |
the mutant shows altered kinetics compared to the wild-type enzyme |
725460 |