EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   7.6.2.2 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
26828064 |
Small Intestine but Not Liver Lysophosphatidylcholine Acyltransferase 3 (Lpcat3) Deficiency Has a Dominant Effect on Plasma Lipid Metabolism. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
1
4
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
9144452 |
P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity. |
causal interaction
unassigned |
2
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
9717696 |
Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice. |
causal interaction
unassigned |
4
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
10736562 |
MARCKS: a case of molecular exaptation? |
causal interaction
unassigned |
4
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
11281547 |
Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice. |
causal interaction
unassigned |
3
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
11984826 |
mdr1a deficiency corrects sterility in Niemann-Pick C1 protein deficient female mice. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
12536246 |
Sestamibi is a substrate for MDR1 and MDR2 P-glycoprotein genes. |
ongoing research
unassigned |
4
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
14636316 |
Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats. |
causal interaction
unassigned |
3
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
14712343 |
Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood-brain barrier of Abcb1a gene knockout mice. |
causal interaction
unassigned |
1
0 |
| 7.6.2.2 | abc-type xenobiotic transporter deficiency |
15618696 |
Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase--effect of cMOAT deficiency on hepatobiliary excretion in rats and of mdr1a/b gene disruption on tissue distribution in mice. |
ongoing research
unassigned |
3
0 |
