EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   7.6.2.16 | abc-type putrescine transporter deficiency |
29906411 |
Dermal Fibroblast SLC3A2 Deficiency Leads to Premature Aging and Loss of Epithelial Homeostasis. |
causal interaction
unassigned |
4
0 |
| 7.6.2.16 | Adenocarcinoma of Lung |
33785413 |
Targeting SLC3A2 subunit of system XC- is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma. |
unassigned |
0 |
| 7.6.2.16 | Asthma |
33341053 |
TMT-based quantitative proteomics reveals suppression of SLC3A2 and ATP1A3 expression contributes to the inhibitory role of acupuncture on airway inflammation in an OVA-induced mouse asthma model. |
causal interaction
ongoing research
unassigned |
3
2
0 |
| 7.6.2.16 | Breast Neoplasms |
33672555 |
xCT-Driven Expression of GPX4 Determines Sensitivity of Breast Cancer Cells to Ferroptosis Inducers. |
causal interaction
unassigned |
3
0 |
| 7.6.2.16 | Carcinoma |
29179459 |
SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer. |
ongoing research
unassigned |
4
0 |
| 7.6.2.16 | Carcinoma |
30670494 |
The CD98 heavy chain is a marker and regulator of head and neck squamous cell carcinoma radiosensitivity. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
| 7.6.2.16 | Carcinoma |
31276435 |
SLC3A2/CD98hc, autophagy and tumor radioresistance: a link confirmed. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
1
3 |
| 7.6.2.16 | Carcinoma, Hepatocellular |
9024798 |
Loss of intracellular putrescine pool-size regulation induces apoptosis. |
ongoing research
unassigned |
4
0 |
| 7.6.2.16 | Carcinoma, Hepatocellular |
34318944 |
IFN?-mediated repression of system xc- drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells. |
diagnostic usage
unassigned |
1
0 |
| 7.6.2.16 | Carcinoma, Squamous Cell |
30670494 |
The CD98 heavy chain is a marker and regulator of head and neck squamous cell carcinoma radiosensitivity. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
