EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    6.4.1.2 | acetyl-coa carboxylase deficiency |
6114432 |
Acetyl-CoA carboxylase deficiency: an inborn error of de novo fatty acid synthesis. |
ongoing research
unassigned |
2
0 |
| 6.4.1.2 | Acne Vulgaris |
31092695 |
Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition. |
unassigned |
0 |
| 6.4.1.2 | Adenocarcinoma |
6106506 |
Tissue specificity for the effect of estrogen on lipogenic activity in male and female rats. |
causal interaction
unassigned |
1
0 |
| 6.4.1.2 | Adenocarcinoma |
6130760 |
Studies on acetyl-CoA carboxylase and fatty acid synthase from rat mammary gland and mammary tumours. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 6.4.1.2 | Adenocarcinoma |
23159620 |
Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. |
ongoing research
unassigned |
3
0 |
| 6.4.1.2 | Adenocarcinoma |
24091913 |
Overexpressing TNF-Alpha in Pancreatic Ductal Adenocarcinoma Cells and Fibroblasts Modifies Cell Survival and Reduces Fatty Acid Synthesis via Downregulation of Sterol Regulatory Element Binding Protein-1 and Activation of Acetyl CoA Carboxylase. |
causal interaction
ongoing research
unassigned |
1
3
0 |
| 6.4.1.2 | Alzheimer Disease |
32075509 |
AMPK activation does not enhance autophagy in neurons in contrast to MTORC1 inhibition: different impact on ?-amyloid clearance. |
unassigned |
0 |
| 6.4.1.2 | Asthma |
32048254 |
Different effects of acetyl-CoA carboxylase inhibitor TOFA on airway inflammation and airway resistance in a mice model of asthma. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
1
0 |
| 6.4.1.2 | Ataxia Telangiectasia |
31983282 |
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 6.4.1.2 | Azotemia |
19357177 |
Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney. |
ongoing research
unassigned |
1
0 |
