EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   2.7.11.20 | Neoplasms |
22020937 |
1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. |
therapeutic application
unassigned |
4
0 |
| 2.7.11.20 | Neoplasms |
24732796 |
A conserved loop in the catalytic domain of eukaryotic elongation factor 2 kinase plays a key role in its substrate specificity. |
causal interaction
unassigned |
3
0 |
| 2.7.11.20 | Starvation |
19221463 |
A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses. |
therapeutic application
unassigned |
2
0 |
| 2.7.11.20 | Neoplasms |
27818922 |
A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
2
4
2
0 |
| 2.7.11.20 | Breast Neoplasms |
23102376 |
Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
| 2.7.11.20 | Adenocarcinoma of Lung |
30890561 |
Ablation of elongation factor 2 kinase enhances heat-shock protein 90 chaperone expression and protects cells under proteotoxic stress. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 2.7.11.20 | Neoplasms |
30890561 |
Ablation of elongation factor 2 kinase enhances heat-shock protein 90 chaperone expression and protects cells under proteotoxic stress. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 2.7.11.20 | Starvation |
34004054 |
Activation of GCN2 in macrophages promotes white adipose tissue browning and lipolysis under leucine deprivation. |
unassigned |
0 |
| 2.7.11.20 | Starvation |
28771613 |
Activation of Gcn2 in response to different stresses. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 2.7.11.20 | Breast Neoplasms |
10408694 |
Activity and regulation by growth factors of calmodulin-dependent protein kinase III (elongation factor 2-kinase) in human breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
