EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.4.1.47 | Ataxia |
16551741 |
Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons. |
unassigned |
0 |
| 2.4.1.47 | Breast Neoplasms |
20648017 |
Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 2.4.1.47 | Breast Neoplasms |
26528430 |
Association between CLN3 (Neuronal Ceroid Lipofuscinosis, CLN3 Type) Gene Expression and Clinical Characteristics of Breast Cancer Patients. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
| 2.4.1.47 | Breast Neoplasms |
29728441 |
Inhibition of UGT8 suppresses basal-like breast cancer progression by attenuating sulfatide-?V?5 axis. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
3
1
0 |
| 2.4.1.47 | Demyelinating Diseases |
9387870 |
Tellurium causes dose-dependent coordinate down-regulation of myelin gene expression. |
causal interaction
diagnostic usage
unassigned |
1
4
0 |
| 2.4.1.47 | Demyelinating Diseases |
15968630 |
Oligodendrocyte-specific ceramide galactosyltransferase (CGT) expression phenotypically rescues CGT-deficient mice and demonstrates that CGT activity does not limit brain galactosylceramide level. |
causal interaction
unassigned |
1
0 |
| 2.4.1.47 | Demyelinating Diseases |
16528405 |
Oligodendrocytes assist in the maintenance of sodium channel clusters independent of the myelin sheath. |
ongoing research
unassigned |
1
0 |
| 2.4.1.47 | Galactosemias |
16125333 |
The molecular relationship between deficient UDP-galactose uridyl transferase (GALT) and ceramide galactosyltransferase (CGT) enzyme function: a possible cause for poor long-term prognosis in classic galactosemia. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 2.4.1.47 | Leukodystrophy, Globoid Cell |
34262084 |
Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.4.1.47 | Leukodystrophy, Metachromatic |
34262084 |
Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
