EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.1.1.357 | Adenocarcinoma |
15983384 |
High-resolution genomic profiles of human lung cancer. |
causal interaction
diagnostic usage
unassigned |
2
2
0 |
| 2.1.1.357 | Adenocarcinoma |
21385930 |
The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 2.1.1.357 | Adenocarcinoma |
24051013 |
PPAPDC1B and WHSC1L1 Are Common Drivers of the 8p11-12 Amplicon, Not Only in Breast Tumors But also in Pancreatic Adenocarcinomas and Lung Tumors. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
3
4
1 |
| 2.1.1.357 | Bone Diseases |
25887188 |
Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma. |
causal interaction
diagnostic usage
unassigned |
3
3
0 |
| 2.1.1.357 | Breast Neoplasms |
19390626 |
Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
4
0 |
| 2.1.1.357 | Breast Neoplasms |
20940404 |
Transforming properties of 8p11-12 amplified genes in human breast cancer. |
unassigned |
0 |
| 2.1.1.357 | Breast Neoplasms |
24051013 |
PPAPDC1B and WHSC1L1 Are Common Drivers of the 8p11-12 Amplicon, Not Only in Breast Tumors But also in Pancreatic Adenocarcinomas and Lung Tumors. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
3
4
1 |
| 2.1.1.357 | Breast Neoplasms |
24874954 |
An epigenomic approach to therapy for tamoxifen-resistant breast cancer. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 2.1.1.357 | Breast Neoplasms |
27005559 |
Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ER? in SUM-44 breast cancer cells and is associated with ER? over-expression in breast cancer. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
1
0 |
| 2.1.1.357 | Breast Neoplasms |
30936716 |
Downregulation of MMSET impairs breast cancer proliferation and metastasis through inhibiting Wnt/?-catenin signaling. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
4 |
