EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.99.29 | Adenocarcinoma |
25261239 |
A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer. |
unassigned |
0 |
| 1.14.99.29 | Glioblastoma |
22927971 |
Expression of Eukaryotic Initiation Factor 5A and Hypusine Forming Enzymes in Glioblastoma Patient Samples: Implications for New Targeted Therapies. |
unassigned |
0 |
| 1.14.99.29 | Leishmaniasis |
25769972 |
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review. |
therapeutic application
unassigned |
1
0 |
| 1.14.99.29 | Malaria |
23505486 |
Deoxyhypusine Hydroxylase from Plasmodium vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
1
0 |
| 1.14.99.29 | Malaria |
23943044 |
Chemical profiling of deoxyhypusine hydroxylase inhibitors for antimalarial therapy. |
causal interaction
therapeutic application
unassigned |
1
2
0 |
| 1.14.99.29 | Malaria |
27516964 |
A suggested vital function for eIF-5A and dhs genes during murine malaria blood-stage infection. |
unassigned |
0 |
| 1.14.99.29 | Neoplasms |
24178473 |
The polyamine-derived amino acid hypusine: its post-translational formation in eIF-5A and its role in cell proliferation. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 1.14.99.29 | Neoplasms |
24220243 |
Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation. |
therapeutic application
unassigned |
1
0 |
| 1.14.99.29 | Prostatic Neoplasms |
22908221 |
Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells. |
diagnostic usage
unassigned |
1
0 |
