EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
20729857 |
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
23967333 |
H3K27 Demethylase, JMJD3, Regulates Fragmentation of Spermatogonial Cysts. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
25531312 |
Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
4
1
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
26699812 |
Cu,Zn-SOD-mediated Redox Regulation of Jmjd3 Modulates Macrophage Polarization and Pulmonary Fibrosis. |
causal interaction
unassigned |
2
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
28323958 |
JMJD3 is crucial for female AVPV RIP-Cre neuron controlled kisspeptin-estrogen feedback loop and reproductive function. |
causal interaction
unassigned |
4
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
29908485 |
Myeloid Kdm6b deficiency results in advanced atherosclerosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
1
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
31393857 |
JMJD3 regulates CD4 T cell trafficking by targeting actin cytoskeleton regulatory gene Pdlim4. |
unassigned |
0 |
| 1.14.18.B1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase deficiency |
34542160 |
JMJD3 deficiency alleviates lipopolysaccharide?induced acute lung injury by inhibiting alveolar epithelial ferroptosis in a Nrf2?dependent manner. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
| 1.14.18.B1 | Acquired Immunodeficiency Syndrome |
28328977 |
JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors. |
diagnostic usage
ongoing research
unassigned |
2
2
0 |
| 1.14.18.B1 | Acrocephalosyndactylia |
33298158 |
Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
