EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    1.14.14.17 | Neuroendocrine Tumors |
30626880 |
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition. |
unassigned |
0 |
| 1.14.14.17 | Tinea |
34097482 |
Checkerboard Analysis To Evaluate Synergistic Combinations of Existing Antifungal Drugs and Propylene Glycol Monocaprylate in Isolates from Recalcitrant Tinea Corporis and Cruris Patients Harboring Squalene Epoxidase Gene Mutation. |
ongoing research
unassigned |
2
0 |
| 1.14.14.17 | Lymphoma |
33067202 |
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 1.14.14.17 | Neoplasms |
33067202 |
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 1.14.14.17 | Neoplasms |
27325648 |
Cholesterol Metabolism and Prostate Cancer Lethality. |
diagnostic usage
unassigned |
2
0 |
| 1.14.14.17 | Cholelithiasis |
14684588 |
Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse. |
ongoing research
therapeutic application
unassigned |
3
3
0 |
| 1.14.14.17 | Gallstones |
14684588 |
Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse. |
ongoing research
therapeutic application
unassigned |
3
3
0 |
| 1.14.14.17 | Prostatic Neoplasms |
28595267 |
Cholesterol uptake and regulation in high-grade and lethal prostate cancers. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
4
1
0 |
| 1.14.14.17 | Onychomycosis |
34297623 |
Drug Sensitivity Profile of Fungi Isolated from Onychomycosis Patients and Evaluation of Squalene Epoxidase Mutation in One Terbinafine-Resistant Trichophyton mentagrophytes Species. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 1.14.14.17 | Hypercholesterolemia |
1649182 |
Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
