EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.14.14.154 | Amebiasis |
26014948 |
Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14?-Demethylase (CYP51). |
therapeutic application
unassigned |
4
0 |
| 1.14.14.154 | Antley-Bixler Syndrome Phenotype |
15483095 |
Cytochrome P450 oxidoreductase gene mutations and Antley-Bixler syndrome with abnormal genitalia and/or impaired steroidogenesis: molecular and clinical studies in 10 patients. |
causal interaction
diagnostic usage
unassigned |
3
4
0 |
| 1.14.14.154 | Antley-Bixler Syndrome Phenotype |
21247357 |
Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
2
0 |
| 1.14.14.154 | Antley-Bixler Syndrome Phenotype |
22111624 |
Cytochrome P450s in the synthesis of cholesterol and bile acids - from mouse models to human diseases. |
causal interaction
unassigned |
4
0 |
| 1.14.14.154 | Aspergillosis |
17352532 |
Essential gene identification and drug target prioritization in Aspergillus fumigatus. |
therapeutic application
unassigned |
2
0 |
| 1.14.14.154 | Aspergillosis |
20733046 |
Impact of cyp51A mutations on the pharmacokinetic and pharmacodynamic properties of voriconazole in a murine model of disseminated aspergillosis. |
ongoing research
unassigned |
2
0 |
| 1.14.14.154 | Aspergillosis |
22526309 |
Development of novel PCR assays to detect azole resistance-mediating mutations of the Aspergillus fumigatus cyp51A gene in primary clinical samples from neutropenic patients. |
causal interaction
diagnostic usage
unassigned |
1
3
0 |
| 1.14.14.154 | Aspergillosis |
23189538 |
Azole resistance in Aspergillus: an emerging problem? |
causal interaction
unassigned |
1
0 |
| 1.14.14.154 | Aspergillosis |
23991080 |
Composite Survival Index to Compare Virulence Changes in Azole-Resistant Aspergillus fumigatus Clinical Isolates. |
unassigned |
0 |
| 1.14.14.154 | Aspergillosis |
25072733 |
Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013. |
diagnostic usage
therapeutic application
unassigned |
2
1
0 |
