EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.11.2 | Acute Kidney Injury |
34515168 |
Role of Endothelial Prolyl-4-Hydroxylase Domain Protein/Hypoxia-Inducible Factor Axis in Acute Kidney Injury. |
ongoing research
unassigned |
1
0 |
| 1.14.11.2 | Adenocarcinoma |
31239153 |
P4HA1/HIF1? feedback loop drives the glycolytic and malignant phenotypes of pancreatic cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
1
3
0 |
| 1.14.11.2 | Adenocarcinoma of Lung |
12114434 |
Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors. |
diagnostic usage
unassigned |
3
0 |
| 1.14.11.2 | Adenocarcinoma of Lung |
33299876 |
Overexpression of P4HA1 Is Correlated with Poor Survival and Immune Infiltrates in Lung Adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
3
0 |
| 1.14.11.2 | Adenocarcinoma of Lung |
34049151 |
Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
3
4 |
| 1.14.11.2 | Alzheimer Disease |
19659431 |
HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease. |
causal interaction
unassigned |
2
0 |
| 1.14.11.2 | Anemia |
19183336 |
In vivo functions of the prolyl-4-hydroxylase domain oxygen sensors: direct route to the treatment of anaemia and the protection of ischaemic tissues. |
therapeutic application
unassigned |
3
0 |
| 1.14.11.2 | Anemia |
19737309 |
The prolyl-hydroxylase EGLN3 and not EGLN1 is inactivated by methylation in plasma cell neoplasia. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
3
1
0 |
| 1.14.11.2 | Anemia |
21372172 |
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective HIF prolyl hydroxylase (PHD) inhibitor. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 1.14.11.2 | Anemia |
21406036 |
HIF prolyl hydroxylase inhibitors for anemia. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
